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| Product Name: |
Anti-EGFR (L858Q) Mouse Monoclonal Antibody
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| Related proudcts |
antibody, |
| Specifications |
26221 |
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Catalog Number: 26221
Gene Symbol: EGFR/HER1/ERBB1
Description: Anti-EGFR (L858Q) Mouse Monoclonal Antibody
Background: EGFR is a receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. It activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. Defects in EGFR are associated with lung cancer (LNCR).
Immunogen: A synthetic peptide from the internal region of EGFR which includes the mutation of L858Q, human origin.
Applications: ELISA, WB, IF, IHC
Recommended Dilutions:
ELISA: 1:1000-1:5000
WB: 1:500-1:1000
IHC: 1:50-1:100
Concentration: 1 mg/ml
Host: mouse
Format: Liquid
Clonality: Monoclonal
Isotype:
Purity: Purified from ascites
Storage buffer:
Preservative: no
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity: Recognizes EGFR (L858Q), but not wild type EGFR protein from vertebrates.
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
| Company: |
NewEast Biosciences
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| Contact: |
Mr. liu David |
| Address: |
1150 First Avenue, Suite 501A |
| Postcode: |
19406 |
| Tel: |
6109452007 |
| Fax: |
877-271-1876 |
| E-mail: |
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