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| Product Name: |
Anti-MEK1 (N382H) Mouse Monoclonal Antibody
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| Supply Ability: |
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| Related proudcts |
antibody, |
| Specifications |
26270 |
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Catalog Number: 26270
Gene Symbol: MAP2K1; MAPKK1; MEK1; MKK1; PRKMK1
Description: Anti-MEK1 (N382H) Mouse Monoclonal Antibody
Background: MEK1 (also known as extracellular signal-regulated kinases, ERKs) plays important role in the MAP kinase cascade, which transduces multiple extracellular signals to control cell growth, proliferation and differentiation. Activated upon growth factors stimulation, MEK1 phosphorylates MAPK3/ERK1 and MAPK1/ERK2, thus activates the MAP pathway and regulates transcription. Abnormal of the MEK1 protein, including point mutations, are implicated in diseases such as cardiofaciocutaneous syndrome (CFC) and melanoma.
Immunogen: A synthetic peptide from the internal region of MEK1 which includes the mutation of N382H, human origin.
Applications: ELISA, WB, IHC
Recommended Dilutions:
ELISA: 1:1000-1:5000
WB: 1:500-1:1000
IHC: 1:50-1:100
Concentration: 1 mg/ml
Host: Mouse
Format: Liquid
Clonality:
Isotype:
Purity:
Storage buffer:
Preservative: no
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity: Recognizes N382H mutant, but not wild-type MEK1 of vertebrates.
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
| Company: |
NewEast Biosciences
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| Contact: |
Mr. liu David |
| Address: |
1150 First Avenue, Suite 501A |
| Postcode: |
19406 |
| Tel: |
6109452007 |
| Fax: |
877-271-1876 |
| E-mail: |
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