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| Product Name: |
Anti-IDH2 (R140Q) Mouse Monoclonal Antibody
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| Related proudcts |
antibody, |
| Specifications |
26165 |
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Catalog Number: 26165
Gene Symbol: IDH2; D2HGA2; ICD-M; IDH; IDHM; IDP; IDPM; mNADP-IDH
Description: Anti-IDH2 (R140Q) Mouse Monoclonal Antibody
Background: Isocitrate dehydrogenase (IDH) catalyzes the oxidative decarboxylation of isocitrate to 2-oxoglutarate. Mutations of Arg-132 in IDH to Cys, His, Leu or Ser abolish magnesium binding and the conversion of isocitrate to alpha-ketoglutarate. Instead, alpha-ketoglutarate is converted to R-2-hydroxyglutarate. Elevated levels of R-2-hydroxyglutarate are correlated with an elevated risk of malignant brain tumors.
Immunogen:
Applications: ELISA, WB, IHC
Recommended Dilutions:
ELISA: 1:1000-1:5000
WB: 1:500-1:1000
IHC: 1:50-1:100
Concentration: 1 mg/ml
Host: Mouse
Format: Liquid
Clonality:
Isotype:
Purity:
Storage buffer:
Preservative: no
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity: Recognizes R140Q mutant, but not wild-type IDH2 of vertebrates.
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
| Company: |
NewEast Biosciences
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| Contact: |
Mr. liu David |
| Address: |
1150 First Avenue, Suite 501A |
| Postcode: |
19406 |
| Tel: |
6109452007 |
| Fax: |
877-271-1876 |
| E-mail: |
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